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Turkiye Klinikleri Journal of Medical Sciences, vol.39, no.1, pp.125-128, 2019 (Scopus)
Intrapancreatic accessory spleen is a relatively uncommon congenital lesion, with a prevalence of 2%; reported in an autopsy series. Radiological differential diagnosis for intra and peripancreatic accessory spleen includes pancreatic neuroendocrine tumors, lymphoepithelial cysts, lymphomas, hypervascular metastases, solid pseudopapillary tumors and pancreatic adenocarcinomas. Accessory spleen is a clinically quiescent entity which is usually asymptomatic. It does not require surgical resection or extra follow up. In a patient with an intra-peripancreatic mass, in order to prevent invasive procedures such as unnecessary surgical resections and to decrease patient morbidity and mortality rates, the endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) cytological diagnosis is mandatory. As this is a very rare entity in routine practice, the cytopathologists should keep it in mind, in the differential diagnoses of a pancreatic mass. In this report, we present a rare case of intrapancreatic accessory spleen which is diagnosed by EUS /FNA cytology, discussing its unique cytomorphological and immunohistochemical characteristics.