Ethanol-induced changes in lipid peroxidation and glutathione content in rat brain

Uysal M., Kutalp G., Özdemirler G., Aykaç G.

Drug and Alcohol Dependence, cilt.23, sa.3, ss.227-230, 1989 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 3
  • Basım Tarihi: 1989
  • Doi Numarası: 10.1016/0376-8716(89)90085-9
  • Dergi Adı: Drug and Alcohol Dependence
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.227-230
  • Anahtar Kelimeler: brain, ethanol, glutathione, lipid peroxidation, liver, rat
  • İstanbul Yeni Yüzyıl Üniversitesi Adresli: Hayır

Özet

The effect of acute and chronic ethanol administration on brain lipid peroxide and glutathione levels was investigated in rats. Acute ethanol administration (5 g/kg, i.p.) led to an increase in lipid peroxide levels and a decrease in glutathione levels in whole brain homogenates without cerebellum. However, there was no change in brain lipid peroxide and glutathione levels of rats chronically treated with ethanol. © 1989.