Chemistry of endemic Tanacetum mucroniferum Hub.-Mor. & Grierson extracts and three new sesquiterpene lactones

SERVİ H., GÖREN N.

Turkish Journal of Chemistry, cilt.43, sa.1, ss.352-358, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.3906/kim-1808-26
  • Dergi Adı: Turkish Journal of Chemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.352-358
  • Anahtar Kelimeler: Coumarin, Flavonoids, Sesquiterpene lactones, Tanacetum mucroniferum, Triterpene
  • İstanbul Yeni Yüzyıl Üniversitesi Adresli: Hayır

Özet

Tanacetum mucroniferum Hub.-Mor. & Grierson was collected from Sakaltutan in Erzincan Province of Turkey. Comparative phytochemical investigation was carried out on the ethyl acetate and methanol extracts of the plant. The secondary metabolites were isolated and purified by chromatographic methods such as column chromatography, medium pressure liquid chromatography, high-performance thin-layer chromatography, and preparative thin-layer chromatography. The extracts of the aerial parts of Tanacetum mucroniferum yielded three new sesquiterpene lactones and some known compounds, namely two sesquiterpene lactones, six flavonoids, three coumarins, and one triterpene. Structures of isolated compounds were determined by IR, UV, 1 H NMR, APT, COSY, HSQC, HMBC, NOESY, and MS (EI, CI) spin decoupling, and some chemical reactions were carried out.