ADP-ribosylation of serum proteins: Elevated levels in neoplastic cases due to altered NAD/ADP-ribose metabolism
Cancer Investigation, cilt.15, sa.3, ss.217-223, 1997 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 15 Sayı: 3
- Basım Tarihi: 1997
- Doi Numarası: 10.3109/07357909709039718
- Dergi Adı: Cancer Investigation
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.217-223
- Anahtar Kelimeler: ADP-ribosylation, NAD glycohydrolase, Neoplastic disease, Serum NAD levels, Serum proteins
- İstanbul Yeni Yüzyıl Üniversitesi Adresli: Hayır
Özet
ADP-ribosylation of human serum proteins was studied in various groups of disorders. In most of these groups, the extent of ADP-ribosylation did not show a divergence from the group of normal controls. Neoplastic diseases revealed, however; a unique group, with more than fivefold increases in ADP- ribosylation levels over the other groups. Blood samples with high levels of ADP-ribosylation revealed, in general, increased serum NAD glycohydrolase activities and low levels of serum NAD.