Effect of 5-methoxytryptophan and 5-methoxytryptamine on the reproductive system of the male golden hamster

Pévet P., Haldat-Misra C., Öcal T.

Journal of Neural Transmission, cilt.51, sa.3-4, ss.303-311, 1981 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 3-4
  • Basım Tarihi: 1981
  • Doi Numarası: 10.1007/bf01248961
  • Dergi Adı: Journal of Neural Transmission
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.303-311
  • İstanbul Yeni Yüzyıl Üniversitesi Adresli: Hayır

Özet

S.c. injections of 25 μg of methoxytryptamine (5-MT) in oil into adult male hamsters given between 4.30 and 5 p.m. (light on from 5 a.m. to 7 p.m.: 14 L/10 D) for 51 consecutive days caused involution of the testes. Similar injections of 5-MT given between 8.30 and 9.30 a.m. completely failed to cause regression of the gonads. Under the same conditions, 5-methoxytryptophan (5-MTP) did not induce gonadal atrophy, neither in the morning nor in the late afternoon. These results indicate that, like melatonin, 5-methoxytryptamine is implicated in the control of the reproductive function. © 1981 Springer-Verlag.