On the nature of cellular ADP-ribosyltransferase from rat liver specific for elongation factor 2

Sayhan, O.; Özdemirli, M.; Nurten, RÜSTEM; Bermek, E.

doi:10.1016/s0006-291x(86)80306-0

On the nature of cellular ADP-ribosyltransferase from rat liver specific for elongation factor 2

Atıf İçin Kopyala

Sayhan O., Özdemirli M., Nurten R., Bermek E.

Biochemical and Biophysical Research Communications, cilt.139, sa.3, ss.1210-1214, 1986 (Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 139 Sayı: 3
Basım Tarihi: 1986
Doi Numarası: 10.1016/s0006-291x(86)80306-0
Dergi Adı: Biochemical and Biophysical Research Communications
Derginin Tarandığı İndeksler: Scopus
Sayfa Sayıları: ss.1210-1214
İstanbul Yeni Yüzyıl Üniversitesi Adresli: Hayır

Özet

A cellular ADP-ribosyltransferase, specific for elongation factor 2 (EF-2), is found in extracts from rat liver. Co-migrating with EF-2 throughout purification, this activity is, moreover, located in the protein bands corresponding to EF-2 after native or sodium dodecyl sulfate polyacrylamide gel electrophoresis. The observed activity is thus implicated to be an inherent property of EF-2. Preincubation of EF-2 with GuoPPCH2Pox inhibits endogenous, but not diphtheria toxin catalyzed ADP-ribosylation. © 1986 Academic Press, Inc.