Respiratory Muscle Endurance in Obesity Hypoventilation Syndrome
Respiratory Care, cilt.67, sa.5, ss.526-533, 2022 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 67 Sayı: 5
- Basım Tarihi: 2022
- Doi Numarası: 10.4187/respcare.09338
- Dergi Adı: Respiratory Care
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE, DIALNET
- Sayfa Sayıları: ss.526-533
- Anahtar Kelimeler: fatigue, muscle endurance, obesity hypoventilation syndrome, quality of life, respiratory muscle, sleep
- İstanbul Yeni Yüzyıl Üniversitesi Adresli: Hayır
Özet
BACKGROUND: An increase in respiratory work load and resistance to respiration cause a decrease in respiratory muscle endurance (RME) in patients with obesity hypoventilation syndrome (OHS). We aimed to evaluate and compare RME in subjects with OHS and a control group using an incremental load test and compare the RME of subjects with OHS in whom noninvasive ventilation (NIV) was and was not used. METHODS: Forty subjects with OHS (divided according to body mass index [BMI] as group I: 30–40 kg/m2; and group II: 6 40 kg/m2) and 20 subjects with obesity (control group: 30–40 kg/m2) were included in the study. RME was evaluated using the incremental load test, and respiratory muscle strength (RMS) was evaluated using mouth pressure measurements. The 6-min walk test, Epworth Sleepiness Scale (ESS), Pittsburgh Sleep Quality Index (PSQI), Fatigue Severity Scale (FSS), EQ-5D Health-Related Quality of Life Questionnaire (EQ-5D), and the Obesity and Weight-Loss Quality of Life Instrument (OWLQOL) were performed. RESULTS: RME and RMS (%) in group I were lower than the control group (P 5 .001, P 5 .005, and P 5 .001, respec-tively). No significant difference was found between the 3 groups in terms of 6-min walk distance (6MWD) percentage predicted values (P 5 .98). RME in the NIV user group was higher than the non-user group (P 5 .006). ESS, total PSQI, and FSS scores in the control group were less than group I (P 5 .01, P 5 .009, and P 5 .005, respectively) and group II (P 5 .01, P < .001, and P < .001, respectively). The EQ-5D scores of the control group were higher than group II only (P 5 .005 and P 5 .005, respectively). There were no differences in OWLQOL between the groups (P 5 .053). CONCLUSIONS: RME was low in subjects with OHS but higher in those who used NIV. The incremental load test could be performed easily and safely in a clinic setting.