Akademik Veri Yönetim Sistemi
PATHOGENS, cilt.14, sa.4, ss.1-15, 2025 (SCI-Expanded)
Fusarium graminearum is a common plant
pathogen among cereals worldwide. The application of chemical antifungal
compounds is the most frequently used method in controlling F. graminearum.
However, its excessive use and the genomic plasticity of the fungal
genome lead to increased resistance levels to these chemical antifungal
compounds. In this context, plant-derived compounds might play a role in
protecting against Fusarium head blight (FHB) and crown rot (CR) as an
alternative. In this study, we aimed to examine the antifungal effects
of an essential oil obtained from Rosa damascena Mill. on the plant pathogen F. graminearum
using molecular and analytical methods. The chemical composition of the
essential oil was determined by GC-MS. The half effective concentration
(EC50) value of R. damascena essential oil (REO) for F. graminearum was determined as 604.25 µg mL−1. Water-soluble tetrazolium 1 (WST-1) analyses revealed that REO caused cytotoxicity in F. graminearum. The potential oxidative stress and autophagic cell death capacity of REO towards F. graminearum
was revealed via gene expression analysis and fluorescence microscopy.
It was also revealed that, due to the plant-protective effect of REO,
the disease severity of treated plants decreased by up to 27.78% in
juvenile wheat seedlings infected by F. graminearum. Our data show that R. damascena essential oil might be used as an alternative natural ingredient in the field of plant protection.