The hepatic lipid peroxidation, copper and fibrosis in cholestatic rats
Pharmacological Research, cilt.21, sa.6, ss.701-706, 1989 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 21 Sayı: 6
- Basım Tarihi: 1989
- Doi Numarası: 10.1016/1043-6618(89)90229-6
- Dergi Adı: Pharmacological Research
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.701-706
- Anahtar Kelimeler: cholestasis, copper, fibrosis, lipid peroxidation
- İstanbul Yeni Yüzyıl Üniversitesi Adresli: Hayır
Özet
Hepatic lipid peroxidation was shown to be stimulated in the livers of cholestatic rats with increased hydroxyproline levels. In another group, cholestatic rats were fed with a copper-supplemented diet to increase hepatic copper levels. Although liver copper concentrations increased about 16-fold in copper supplemented cholestatic rats compared to normally fed cholestatic rats, no change was observed either in hepatic lipid peroxidation or in hydroxyproline levels. © 1989.