Peroxidation status of erythrocytes and apolipoprotein B containing lipoproteins in hypercholesterolemic subjects
International Journal for Vitamin and Nutrition Research, cilt.67, sa.2, ss.130-133, 1997 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 67 Sayı: 2
- Basım Tarihi: 1997
- Dergi Adı: International Journal for Vitamin and Nutrition Research
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.130-133
- İstanbul Yeni Yüzyıl Üniversitesi Adresli: Hayır
Özet
Erythrocyte diene conjugate levels and glutathione peroxidase and superoxide dismutase activities were found unchanged in hypercholesterolemic subjects with plasma cholesterol levels above 240 mg/dl as compared to normocholesterolemics (below 200 mg/dl). However, the susceptibility of VLDL + LDL, apolipoprotein B containing lipoproteins to copper-induced peroxidation and plasma endogenous malondialdehyde levels were increased in hypercholesterolemics. These results indicate that hypercholesterolemia is associated with increased susceptibility of VLDL + LDL to lipid peroxidation.