Peroxidation status of erythrocytes and apolipoprotein B containing lipoproteins in hypercholesterolemic subjects

Özdemirler G., Öztezcan S., Toker G., Uysal M.

International Journal for Vitamin and Nutrition Research, cilt.67, sa.2, ss.130-133, 1997 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 67 Sayı: 2
  • Basım Tarihi: 1997
  • Dergi Adı: International Journal for Vitamin and Nutrition Research
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.130-133
  • İstanbul Yeni Yüzyıl Üniversitesi Adresli: Hayır

Özet

Erythrocyte diene conjugate levels and glutathione peroxidase and superoxide dismutase activities were found unchanged in hypercholesterolemic subjects with plasma cholesterol levels above 240 mg/dl as compared to normocholesterolemics (below 200 mg/dl). However, the susceptibility of VLDL + LDL, apolipoprotein B containing lipoproteins to copper-induced peroxidation and plasma endogenous malondialdehyde levels were increased in hypercholesterolemics. These results indicate that hypercholesterolemia is associated with increased susceptibility of VLDL + LDL to lipid peroxidation.