Peroxidation status of erythrocytes and apolipoprotein B containing lipoproteins in hypercholesterolemic subjects

Özdemirler G., Öztezcan S., Toker G., Uysal M.

International Journal for Vitamin and Nutrition Research, vol.67, no.2, pp.130-133, 1997 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 67 Issue: 2
  • Publication Date: 1997
  • Journal Name: International Journal for Vitamin and Nutrition Research
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.130-133
  • İstanbul Yeni Yüzyıl University Affiliated: No

Abstract

Erythrocyte diene conjugate levels and glutathione peroxidase and superoxide dismutase activities were found unchanged in hypercholesterolemic subjects with plasma cholesterol levels above 240 mg/dl as compared to normocholesterolemics (below 200 mg/dl). However, the susceptibility of VLDL + LDL, apolipoprotein B containing lipoproteins to copper-induced peroxidation and plasma endogenous malondialdehyde levels were increased in hypercholesterolemics. These results indicate that hypercholesterolemia is associated with increased susceptibility of VLDL + LDL to lipid peroxidation.