Excessive effects of benzodiazepines in patients with cirrhosis of the liver: A pharmacodynamic or a pharmacokinetic problem?


Fisch H., BAKTIR G., Karlagenis G., Bircher J.

Pharmacopsychiatry, vol.19, no.1, pp.14, 1986 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 1
  • Publication Date: 1986
  • Doi Number: 10.1055/s-2007-1017141
  • Journal Name: Pharmacopsychiatry
  • Journal Indexes: Scopus
  • Page Numbers: pp.14
  • İstanbul Yeni Yüzyıl University Affiliated: Yes

Abstract

Disproportionate sedation may result from hypersensitivity of the brain, whereas prolonged sedation may be due to both impaired drug metabolism and hypersensitivity of the brain.