Excessive effects of benzodiazepines in patients with cirrhosis of the liver: A pharmacodynamic or a pharmacokinetic problem?

Fisch, H.U.; BAKTIR, GÜL; Karlagenis, G.; Bircher, J.

doi:10.1055/s-2007-1017141

Excessive effects of benzodiazepines in patients with cirrhosis of the liver: A pharmacodynamic or a pharmacokinetic problem?

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Fisch H., BAKTIR G., Karlagenis G., Bircher J.

Pharmacopsychiatry, vol.19, no.1, pp.14, 1986 (Scopus)

Publication Type: Article / Article
Volume: 19 Issue: 1
Publication Date: 1986
Doi Number: 10.1055/s-2007-1017141
Journal Name: Pharmacopsychiatry
Journal Indexes: Scopus
Page Numbers: pp.14
İstanbul Yeni Yüzyıl University Affiliated: Yes

Abstract

Disproportionate sedation may result from hypersensitivity of the brain, whereas prolonged sedation may be due to both impaired drug metabolism and hypersensitivity of the brain.