The independency of an intact pineal gland of the inhibition by 5-methoxytryptamine of the reproductive organs in the male hamster
Journal of Neural Transmission, cilt.52, sa.1-2, ss.95-106, 1981 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 52 Sayı: 1-2
- Basım Tarihi: 1981
- Doi Numarası: 10.1007/bf01253101
- Dergi Adı: Journal of Neural Transmission
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.95-106
- İstanbul Yeni Yüzyıl Üniversitesi Adresli: Hayır
Özet
Subcutaneous injections of 25 μg of 5-methoxytryptamine (5-MT) in oil into intact and pinealectomized male hamsters given between 4.30 p.m. and 5 p.m. (light on from 5 a.m. to 7 p.m.; 14 L/10 D) for 54 consecutive days caused involution of the testes. 5-MT, however, is more effective when the pineal is present. These results indicate that melatonin is not the only pineal factor inducing gonadal atrophy in the hamster. 5-MT seems even more effective than melatonin in so far as it is, contrary to melatonin under the same experimental conditions, also effective in the absence of the pineal. Like melatonin, 5-MT appears to be implicated in the control of the reproductive function. © 1981 Springer-Verlag.